Endocrine Abstracts

Hirsutism, development of terminal body hair in women in unexpected areas, may result from different etiologies; 4.3% being nonclassical congenital adrenal hyperplasia (NCCAH) and acromegaly being one of the rarests. We here present a severe hirsutism case with acromegaly and NCCAH.Case: A 30-year-old woman with headache and visual field abnormalities was consultated by our clinic about her cranial imaging revealing a macroadenoma in pituitary localizati...

Introduction: Subacute thyroiditis is an iflammatory disease of the thyroid gland characterized by pain, tenderness and swelling in the neck. Less frequently, it may present with painless or silent thyroiditis that occurs spontaneously or in the postpartum period. In a few studies in the literature, urinary iodine was reported to be high in patients with postpartum thyroiditis, but it was not evaluated in patients with subacute thyroiditis. We aimed to evaluate urinary iodine ...

Anaemia prevalence is reported between 5 and 31.8% in patients with PHPT. Anaemia in PHPT shows correlations with serum calcium, PTH, alkaline phosphatase levels, severity of the bone disease and PHPT duration. In this study we compared pre-operative and post-operative haemogram parameters of patients with PHPT who received a parathyroidectomy at our department. We determined the prevelance of pre-operative anaemia, thrombocytopenia, neutropenia and observed if any of this par...

Introduction: Neutrophil/lymphocyte ratio (NLR) is an indicative of the acute phase response. It is a significant indicator of the systemic inflammation, and considered as a poor prognosis indicator in various disease. We aimed to evaluate NLR and its determinants in acromegaly patients.Patients and methods: A retrospective chart review of 40 patients with acromegaly and 45 age and sex matched healthy individuals was performed. Patients with active infec...

Introduction: Pituitary involvement has been rarely reported during the course of hematological diseases like thalessemia, Langerhans-cell histiocytosis and lymphoma. We here present a case of chronic myeloid leukemia (CML) with pituitary involvement, in which central diabetes insipidus (DI) was the first sign of progression to accelerated phase.Case report: A 61-year-old man was consultated by our clinic due to polyuria with 6000 ml daily urine output. ...

Introduction: The increased mortality in acromegaly is mainly related to cardiovascular, respiratory and neoplastic complications; neoplasms being responsible in 15%. Although most of the thyroid nodules in acromegaly are benign, there are studies revealing an increased ratio of differentiated thyroid cancer in this disease. Medullary thyroid carcinoma (MTC) has not been related with acromegaly so far. In this report, we aimed to present a patient with acromegaly whose thyroid...

Introduction: Involvement of different tissues and organs may be seen during the course of Graves’ disease (GD). We here aimed to present a case with GD and lung mass whose lung lesion disappeared after recieving antithyroid treatment.Case report: A 60 year old man admitted to our hospital with back pain. His thorax computed tomography (CT) revealed a 1.5×3 cm mass in lower right lobe. He was consultated by our clinic preoperatively before thor...

Idiopathic hypoparathyroidism (IHP) is an uncommon disease in which soft tissue calcifications may be seen. We report a case with IHP with asymptomatic hypocalcemia and features of ankylosing spondylitis (AS).Case: A 58-year-old male patient was referred to our department due to incidentally discovered hypocalcemia when admitted with blurred speech, gait and posture abnormalities. He had had a generalized convulsion 19 years ago. On physical examination,...

Silent thyroiditis is characterized by the destructive thyroid inflammation and is considered to be a chronic autoimmune thyroid disease, although the etiology could not have been fully explained. On the other hand, Graves’ disease is autoimmune phenomena as well as silent thyroiditis and silent thyroiditis has been classified as part of the spectrum of Graves’ disease. Although, the thyroid stimulating antibody (TSAb) are found positive in most of Graves’ disea...

Introduction: Vitamin D deficiency may be an important predisposing factor for infections as well as autoimmune diseases in old individuals. Neutrophil/lymphocyte ratio (NLR), is a meaningful indicator of inflammation throughout the body. In this study we aimed to show, whether or not a relationship exists between vitamin D levels and NLR in patients older than 65 years.Materials and method: Data of 82 patients over 65 years of age was retrospectively ex...